Tamanoi Lab, iCeMS, Kyoto University

Welcome to Tamanoi Lab!

We research on nanoparticles and cancer therapy. Nanoparticles are attractive materials for delivery of anticancer drugs. We are focusing on mesoporous silica nanoparticles (MSN) that could contribute to prevention of side effect of cancer chemo therapy. MSN has a drug loading capacity and enables specific drug accumulation. We are also developing chicken egg tumor model.


News!!! QNM 2nd symposium

2nd QNM symposium will be held on Friday, April 17th! It has been just decided! We hope much more people participate in! A detail will be gradually announced at time it's decided. Please check our news out!

第2回QNMシンポジウムの開催が決定しました!日にちは4月17日金曜日です。皆様、予定を空けておいてくださいね。 詳細は決まり次第当ウェブサイト上でも随時お知らせしていきますので、どうぞお見逃しなく!!

Latest Press Release!!

We found that cancer cells can be killed by the Auger therapy using monochromatic X-ray and gadolinium-loaded nanoparticles. The key is to put gadolinium close to cancer cell nucleus. Usual X-ray therapy affects normal cells or the efficiency is diminished by absorption at the body surface. We believe that this new type of X-ray therapy could decrease adverse effect of current radiation therapy. On top of this, our therapy can amplify X-ray effect at the site of tumors.


【Scientific Reports】https://www.nature.com/articles/s41598-019-49978-1

【iCeMS English】https://www.icems.kyoto-u.ac.jp/en/news/4934

【iCeMS 日本語】https://www.icems.kyoto-u.ac.jp/ja/news/4930

このほか、日刊工業新聞、News Medical 等でも取り上げていただきました。ありがとうございます!


Latest Publication

Jikken Igaku Bessatsu"患者由来がんモデルを用いたがん研究実践ガイド~CDX・スフェロイド・オルガノイド・PDX/PDOXを網羅 : 臨床検体の取り扱い指針から樹立プロトコールと入手法まで(Practical Guide for Cancer Research using Patient-Derived Experimental Model) " has been published from Yodosha. Ms. Komatsu, Mr. Matsumoto, Prof. Tamanoi are in charge of the chapter "Patient-Derived Chicken Egg : PDcE".

羊土社より「実験医学別冊『患者由来がんモデルを用いたがん研究実践ガイド~CDX・スフェロイド・オルガノイド・PDX/PDOXを網羅 : 臨床検体の取り扱い指針から樹立プロトコールと入手法まで』が発行されました。患者由来がんモデルの導入から実践まで網羅した1冊で、小松技術補佐員、松本助教、玉野井教授は「がんの鶏卵モデル」の章を担当しています。

▼Mesoporous Silica Nanoparticles (MSN) : 130 nm in diameter, 1400 pores/particle


▼Biodegradable Periodic Mesoporous Organosilica (BPMO)


▼Our recent publication relating to this topic


ACS Applied Nano Mat open access 2019.pdf

▼The chicken egg tumor model


▼Patient derived tumor model


▼Collaborating with Prof. Muto


武藤研究室ホームページWebsite of Muto Lab. (only in Japanese)

▼Boron Neutron Capture Therapy(BNCT)


▼Experiment room


▼Making MSN Place